for cheek volume and contour, and 
for lip fullness and enhancement.Inspired by nature
Dynamic By Design
BELOTERO® delivers results so natural, they’re biomimetic3,16,17
Discover a portfolio of biomimetic hyaluronic acid (HA) treatments, each precisely engineered for seamless integration at a specific tissue depth—whether the goal is refining moderate lines, restoring midface volume, or sculpting and enhancing lips.3,7,16-18
Become a ProviderActual BELOTERO BALANCE® (+) patient. Individual results may vary.
ONE TECHNOLOGY. PRECISE PRODUCTS. INTELLIGENT INTEGRATION.
The BELOTERO portfolio is built on a single, proprietary Cohesive Polydensified Matrix (CPM)® technology,3 engineered to mimic skin’s natural structure at different depths.3,16,17 Choose the right product to meet your patients’ goals.
The refiner designed with balanced elasticity and viscosity for refinement and filling of lines and wrinkles (including around the mouth)7
Treats: nasolabial folds, infraorbital hollows, perioral lines7
LASTS UP TO 18 MONTHS20*
The restorer designed with high plasticity, elasticity, and viscosity for ideal reshaping with volume enhancement18
Treats: cheeks, midface18
LASTS UP TO 18 MONTHS22
The sculptor designed with high elasticity and viscosity for lip augmentation19
Treats: lips19
LASTS UP TO 12 MONTHS23
*Among patients who were responders at Week 8 (n=22), 90.2% (20/22) retained treatment response up to 72 weeks after the last injection.20
WHY BELOTERO IS THE RIGHT CHOICE
Defining Biomimetic
The word biomimetic is derived from the ancient Greek words “bios” (life) and “mimesis” (imitate). For your patients, “biomimetic” simply means a filler designed to look, feel, and move like natural skin.
BELOTERO is an HA treatment that mimics the way skin naturally behaves, delivering outcomes based on three core principles:
SEAMLESS
INTEGRATION16
DYNAMIC
ADAPTABILITY16
STRUCTURAL
SUPPORT24,25
Discover how BELOTERO mimics the natural behavior of your skin
Hyaluronic acid or HA is a naturally occurring molecule found in the skin essential for maintaining hydration. With the ability to hold up to 1000 times its weight in water, it helps keep skin plump, smooth, and elastic.
However, as we age, our natural HA levels decline along with other changes in the skin, leading to visible signs of aging such as reduced skin quality, wrinkles, and facial volume loss. This is where HA treatments play a significant role. They are a leading choice to help the skin rehydrate, treat fine lines, deep lines, smooth skin, and regain its natural looking balance.
However, skin is dynamic and complex. Each layer has its own structure and function. An ideal HA formulation should mimic the skin’s natural characteristics and behavior to support natural movement and preserve authentic, dynamic facial expressions.
BELOTERO is purposefully engineered with this in mind. It’s biomimetic by design.
Each product in the BELOTERO portfolio mimics characteristics and behavior of the skin in its distinct tissue layers. They are designed using a patented dual cross linking technology, creating the first and only Cohesive Polydensified Matrix gel that features varying HA densities.
The result?
A broad range of products with targeted properties that shape and support in specific anatomical areas, integrate seamlessly to preserve natural expression even in motion, and distribute evenly for a smooth, refined, and precise finish.
The BELOTERO portfolio enables tailored, personalized treatments from enhancing skin quality to restoring facial contours, delivering natural looking results that move with every expression.
BELOTERO
Biomimetic by Design
Your skin is dynamic, complex, and constantly in motion. Discover the patented CPM technology behind BELOTERO’s distinct HA formulations. Each product is engineered to seamlessly integrate into targeted tissue layers for volume that moves with you.3,7,16-18
TREATMENT AREAS
Get excited about the results you can achieve with BELOTERO BALANCE (+), BELOTERO VOLUME (+), and BELOTERO INTENSE (+) by reviewing the treatment areas where they are designed to be used.
Under-eye hollows/tear trough
Treat under-eye hollows with a filler that spreads and seamlessly integrates into surrounding tissue.3,7,16
Oral commissures
Achieve the sought-after “corner lip lift” to add an instant, youthful tilt.13
Marionette lines
Smooth smile lines with minimal interference to the natural feel and movement of the face.3,10,13,16
Nasolabial folds
Deliver natural-looking results that move with the dermis to correct for deep nasolabial folds.3,7,10,16
Perioral lines
Smooth these thin, vertical lip lines while preserving the expressiveness of the mouth.3,10,13,16
See BELOTERO BALANCE (+) Results
Actual BELOTERO BALANCE (+) patient. Individual results may vary.
Midface
Restore volume to the midface while preserving natural-looking contour.16,18
Cheeks
Enhance cheek definition and fullness with results that seamlessly integrate into skin’s deep layers.13,16,18
See BELOTERO VOLUME (+) Results
Actual BELOTERO BALANCE (+) patient. Individual results may vary.
Lips
Deliver subtle “my lips but better” results patients crave with a formulation specifically designed to look and feel natural to the touch.16,19
See BELOTERO INTENSE (+) Results
Actual BELOTERO BALANCE (+) patient. Individual results may vary.
BELOTERO MARKETING AND EDUCATION
Looking to level up your practice’s marketing efforts? Merz can support you with that and more! Check out downloadable resources available for your patients, and sign in to the Merz Provider Portal where you can access trainings, certifications, and register your practice with the Xperience+® rewards program.
BECOME A PROVIDER
Offer your patients a full spectrum of BELOTERO treatments—from lip enhancements to deep volume restoration—all backed by a single proprietary CPM® technology.7,17-19